Topical timolol: A safer alternative for complicated and un-complicated infantile hemangiomas
نویسندگان
چکیده
منابع مشابه
Topical Timolol Maleate Treatment of Infantile Hemangiomas.
BACKGROUND There has been a dramatic increase in the off-label use of ophthalmic timolol maleate, a β-blocker used for infantile hemangioma (IH) treatment as a topical counterpart to oral propranolol. Its safety and efficacy in a pediatric population with IH have not been evaluated in a large cohort. Our goal was to retrospectively assess timolol's effectiveness, discern characteristics associa...
متن کاملEfficacious Healing of Ulcerated Infantile Hemangiomas Using Topical Timolol
Infantile hemangiomas (IHs) are the most common benign pediatric soft-tissue tumors. Ulceration-the most frequent complication of IH-tends to heal poorly and is associated with pain, bleeding, infection, and scarring. Mainstay treatment modalities include propranolol (β-blocker) and corticosteroids, whose effectiveness is countered by a need for long-term medication and risk of systemic adverse...
متن کاملOral propranolol combined with topical timolol for compound infantile hemangiomas: a retrospective study
Compound infantile hemangiomas (IHs) are problematic and usually require intervention. This retrospective study aimed to introduce a combined therapy of oral propranolol and topical timolol, and evaluate its efficacy and safety. Eighty-nine infants with compound IHs were treated with oral propranolol 2 mg/kg/day divided 2 times per day and timolol maleate 0.5% gel 3 times per day, for at least ...
متن کاملTopical propranolol therapy for infantile hemangiomas.
The nonselective beta-adrenergic receptor antagonist propranolol is an effective therapy for infantile hemangiomas. Systemic propranolol therapy shows a rapid therapeutic effect with good drug tolerability. We report on the efficacy of local application of propranolol ointment in superficial hemangiomas of the skin. In our outpatient department, 45 children with 65 hemangiomas were treated with...
متن کاملTopical timolol 0.5% gel-forming solution for small deep facial infantile hemangiomas.
We report three cases of successful treatment of proliferating deep infantile hemangiomas with topical timolol 0.5% gel-forming solution (GFS) used two to three times daily. We recommend considering timolol as an initial option for small, deep facial hemangiomas that are not causing functional compromise or complications but may have an unsatisfactory cosmetic appearance. In our experience, alb...
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ژورنال
عنوان ژورنال: Indian Journal of Dermatology
سال: 2013
ISSN: 0019-5154
DOI: 10.4103/0019-5154.113997